E23Q (p.Glu23Gln) variant of FOXO3 (Forkhead box protein O3)
E23Q (p.Glu23Gln) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
E23Q (p.Glu23Gln) variant details
- p.Glu23Gln
- gnomAD 6-108561275-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.486
- REVEL 0.37
- MetaLR 0.52
- MetaSVM -0.08
- CADD 22.80
- PolyPhen-2 0.10
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available