E23K (p.Glu23Lys) variant of FOXO3 (Forkhead box protein O3)
E23K (p.Glu23Lys) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
E23K (p.Glu23Lys) variant details
- p.Glu23Lys
- gnomAD 6-108561275-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.504
- REVEL 0.38
- MetaLR 0.59
- MetaSVM 0.03
- CADD 24.40
- PolyPhen-2 0.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available