E23G (p.Glu23Gly) variant of FOXO3 (Forkhead box protein O3)
E23G (p.Glu23Gly) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
E23G (p.Glu23Gly) variant details
- p.Glu23Gly
- gnomAD 6-108561276-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.518
- REVEL 0.46
- MetaLR 0.62
- MetaSVM 0.31
- CADD 24.60
- PolyPhen-2 0.08
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available