E23D (p.Glu23Asp) variant of FOXO3 (Forkhead box protein O3)
E23D (p.Glu23Asp) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
E23D (p.Glu23Asp) variant details
- p.Glu23Asp
- gnomAD 6-108561277-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.395
- REVEL 0.38
- MetaLR 0.60
- MetaSVM 0.11
- CADD 23.00
- PolyPhen-2 0.05
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available