E21V (p.Glu21Val) variant of FOXO3 (Forkhead box protein O3)
E21V (p.Glu21Val) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
E21V (p.Glu21Val) variant details
- p.Glu21Val
- gnomAD 6-108561270-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.495
- REVEL 0.53
- MetaLR 0.45
- MetaSVM -0.02
- CADD 24.70
- PolyPhen-2 0.21
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available