D19G (p.Asp19Gly) variant of FOXO3 (Forkhead box protein O3)
D19G (p.Asp19Gly) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
D19G (p.Asp19Gly) variant details
- p.Asp19Gly
- gnomAD 6-108561264-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.617
- REVEL 0.70
- MetaLR 0.68
- MetaSVM 0.44
- CADD 24.30
- PolyPhen-2 0.14
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available