D19E (p.Asp19Glu) variant of FOXO3 (Forkhead box protein O3)
D19E (p.Asp19Glu) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
D19E (p.Asp19Glu) variant details
- p.Asp19Glu
- gnomAD 6-108561265-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.471
- REVEL 0.49
- MetaLR 0.63
- MetaSVM 0.20
- CADD 23.10
- PolyPhen-2 0.17
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available