C31Y (p.Cys31Tyr) variant of FOXO3 (Forkhead box protein O3)
C31Y (p.Cys31Tyr) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
C31Y (p.Cys31Tyr) variant details
- p.Cys31Tyr
- gnomAD 6-108561300-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.446
- REVEL 0.35
- MetaLR 0.54
- MetaSVM -0.11
- CADD 23.90
- PolyPhen-2 0.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available