C31R (p.Cys31Arg) variant of FOXO3 (Forkhead box protein O3)
C31R (p.Cys31Arg) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
C31R (p.Cys31Arg) variant details
- p.Cys31Arg
- gnomAD 6-108561299-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.543
- REVEL 0.57
- MetaLR 0.63
- MetaSVM 0.35
- CADD 24.40
- PolyPhen-2 0.14
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available