A9G (p.Ala9Gly) variant of FOXO3 (Forkhead box protein O3)
A9G (p.Ala9Gly) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
A9G (p.Ala9Gly) variant details
- p.Ala9Gly
- gnomAD 6-108561234-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.21
- MetaLR 0.30
- MetaSVM -0.72
- CADD 16.00
- PolyPhen-2 0.00
- SIFT 0.47
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available