A4V (p.Ala4Val) variant of FOXO3 (Forkhead box protein O3)
A4V (p.Ala4Val) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
A4V (p.Ala4Val) variant details
- p.Ala4Val
- gnomAD 6-108561219-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.354
- REVEL 0.24
- MetaLR 0.55
- MetaSVM -0.04
- CADD 22.50
- PolyPhen-2 0.04
- SIFT 0.16
- Population evidence available
- Structural context available
- Literature evidence available