A4T (p.Ala4Thr) variant of FOXO3 (Forkhead box protein O3)
A4T (p.Ala4Thr) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
A4T (p.Ala4Thr) variant details
- p.Ala4Thr
- gnomAD 6-108561218-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.30
- MetaLR 0.59
- MetaSVM 0.19
- CADD 21.30
- PolyPhen-2 0.00
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available