A4R (p.Ala4Arg) variant of FOXO3 (Forkhead box protein O3)
A4R (p.Ala4Arg) in FOXO3 (Forkhead box protein O3) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
A4R (p.Ala4Arg) variant details
- p.Ala4Arg
- rs1775773648
- gnomAD 6-108561217-GGCAC
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.639
- CADD 27.70
- Population evidence available
- Structural context available
- Literature evidence available