A45V (p.Ala45Val) variant of FOXO3 (Forkhead box protein O3)
A45V (p.Ala45Val) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
A45V (p.Ala45Val) variant details
- p.Ala45Val
- gnomAD 6-108561342-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.358
- REVEL 0.24
- MetaLR 0.31
- MetaSVM -0.75
- CADD 16.10
- PolyPhen-2 0.00
- SIFT 0.26
- Population evidence available
- Structural context available
- Literature evidence available