A2V (p.Ala2Val) variant of FOXO3 (Forkhead box protein O3)
A2V (p.Ala2Val) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
A2V (p.Ala2Val) variant details
- p.Ala2Val
- cosmic curated COSV59629
- Missense
- Variant Prioritization Score for Impact Estimate 0.565
- REVEL 0.47
- MetaLR 0.62
- MetaSVM 0.19
- CADD 24.00
- PolyPhen-2 0.29
- SIFT 0.00
- Population evidence available
- Structural context available