A2S (p.Ala2Ser) variant of FOXO3 (Forkhead box protein O3)
A2S (p.Ala2Ser) in FOXO3 (Forkhead box protein O3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
A2S (p.Ala2Ser) variant details
- p.Ala2Ser
- gnomAD 6-108561212-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.49
- REVEL 0.35
- MetaLR 0.57
- MetaSVM 0.06
- CADD 23.80
- PolyPhen-2 0.10
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available