Y29L (p.Tyr29Leu) variant of FOS (Protein c-Fos)
Y29L (p.Tyr29Leu) in FOS (Protein c-Fos) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data, published literature, and structural context.
Y29L (p.Tyr29Leu) variant details
- p.Tyr29Leu
- rs1341280530
- gnomAD 14-75279065-CTT-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.779
- CADD 27.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available