Y29H (p.Tyr29His) variant of FOS (Protein c-Fos)
Y29H (p.Tyr29His) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
Y29H (p.Tyr29His) variant details
- p.Tyr29His
- TOPMed rs1297123496
- Missense
- Variant Prioritization Score for Impact Estimate 0.344
- REVEL 0.23
- MetaLR 0.44
- MetaSVM -0.19
- CADD 25.30
- PolyPhen-2 0.99
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 7.2e-06)
- Structural context available