Y29C (p.Tyr29Cys) variant of FOS (Protein c-Fos)
Y29C (p.Tyr29Cys) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
Y29C (p.Tyr29Cys) variant details
- p.Tyr29Cys
- ExAC rs765575516
- TOPMed rs765575516
- gnomAD rs765575516
- Missense
- Variant Prioritization Score for Impact Estimate 0.44
- REVEL 0.41
- MetaLR 0.44
- MetaSVM -0.13
- CADD 26.30
- PolyPhen-2 0.99
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available