W75C (p.Trp75Cys) variant of FOS (Protein c-Fos)
W75C (p.Trp75Cys) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
W75C (p.Trp75Cys) variant details
- p.Trp75Cys
- Ensembl rs1897207533
- Missense
- Variant Prioritization Score for Impact Estimate 0.665
- REVEL 0.60
- MetaLR 0.53
- MetaSVM 0.12
- CADD 33.00
- PolyPhen-2 1.00
- SIFT 1.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available