V82I (p.Val82Ile) variant of FOS (Protein c-Fos)
V82I (p.Val82Ile) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
V82I (p.Val82Ile) variant details
- p.Val82Ile
- gnomAD 14-75279979-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.11
- MetaLR 0.04
- MetaSVM -0.97
- CADD 17.80
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available