V77G (p.Val77Gly) variant of FOS (Protein c-Fos)
V77G (p.Val77Gly) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
V77G (p.Val77Gly) variant details
- p.Val77Gly
- cosmic curated COSV57840
- ExAC rs74685695
- gnomAD rs74685695
- Missense
- Variant Prioritization Score for Impact Estimate 0.614
- REVEL 0.63
- MetaLR 0.40
- MetaSVM -0.18
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.06
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available