V55I (p.Val55Ile) variant of FOS (Protein c-Fos)
V55I (p.Val55Ile) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
V55I (p.Val55Ile) variant details
- p.Val55Ile
- cosmic curated COSV57840
- gnomAD rs1405963852
- Missense
- Variant Prioritization Score for Impact Estimate 0.247
- REVEL 0.07
- MetaLR 0.12
- MetaSVM -1.02
- CADD 21.70
- PolyPhen-2 0.01
- SIFT 0.50
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available