T69N (p.Thr69Asn) variant of FOS (Protein c-Fos)
T69N (p.Thr69Asn) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
T69N (p.Thr69Asn) variant details
- p.Thr69Asn
- gnomAD 14-75279941-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.46
- REVEL 0.26
- MetaLR 0.41
- MetaSVM -0.21
- CADD 25.80
- PolyPhen-2 0.91
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available