T63K (p.Thr63Lys) variant of FOS (Protein c-Fos)
T63K (p.Thr63Lys) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and published literature.
T63K (p.Thr63Lys) variant details
- p.Thr63Lys
- gnomAD 14-75279923-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.553
- REVEL 0.49
- MetaLR 0.43
- MetaSVM -0.13
- CADD 28.30
- PolyPhen-2 1.00
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Literature evidence available