S39T (p.Ser39Thr) variant of FOS (Protein c-Fos)
S39T (p.Ser39Thr) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
S39T (p.Ser39Thr) variant details
- p.Ser39Thr
- TOPMed rs1473426535
- gnomAD rs1473426535
- Missense
- Variant Prioritization Score for Impact Estimate 0.447
- REVEL 0.24
- MetaLR 0.38
- MetaSVM -0.27
- CADD 25.40
- PolyPhen-2 0.93
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available