S28P (p.Ser28Pro) variant of FOS (Protein c-Fos)
S28P (p.Ser28Pro) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
S28P (p.Ser28Pro) variant details
- p.Ser28Pro
- gnomAD 14-75279064-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.07
- MetaLR 0.18
- MetaSVM -0.92
- CADD 23.00
- PolyPhen-2 0.26
- SIFT 0.33
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available