S28F (p.Ser28Phe) variant of FOS (Protein c-Fos)
S28F (p.Ser28Phe) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
S28F (p.Ser28Phe) variant details
- p.Ser28Phe
- 1000Genomes rs563193220
- ExAC rs563193220
- TOPMed rs563193220
- gnomAD rs563193220
- Missense
- Variant Prioritization Score for Impact Estimate 0.371
- REVEL 0.10
- MetaLR 0.30
- MetaSVM -0.45
- CADD 26.40
- PolyPhen-2 0.47
- SIFT 0.21
- Most common in the 1KG:GWD population (allele frequency 0.0043)
- Structural context available