S21Y (p.Ser21Tyr) variant of FOS (Protein c-Fos)
S21Y (p.Ser21Tyr) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
S21Y (p.Ser21Tyr) variant details
- p.Ser21Tyr
- gnomAD 14-75279044-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.567
- REVEL 0.46
- MetaLR 0.62
- MetaSVM 0.33
- CADD 27.70
- PolyPhen-2 0.99
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available