S13P (p.Ser13Pro) variant of FOS (Protein c-Fos)
S13P (p.Ser13Pro) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
S13P (p.Ser13Pro) variant details
- p.Ser13Pro
- gnomAD 14-75279019-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.253
- REVEL 0.15
- MetaLR 0.20
- MetaSVM -0.88
- CADD 17.60
- PolyPhen-2 0.00
- SIFT 0.40
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available
- Literature evidence available