S13L (p.Ser13Leu) variant of FOS (Protein c-Fos)
S13L (p.Ser13Leu) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
S13L (p.Ser13Leu) variant details
- p.Ser13Leu
- ExAC rs768537632
- gnomAD rs768537632
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.14
- MetaLR 0.32
- MetaSVM -0.53
- CADD 23.70
- PolyPhen-2 0.01
- SIFT 0.02
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available