R16S (p.Arg16Ser) variant of FOS (Protein c-Fos)
R16S (p.Arg16Ser) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
R16S (p.Arg16Ser) variant details
- p.Arg16Ser
- ExAC rs774334267
- gnomAD rs774334267
- Missense
- Variant Prioritization Score for Impact Estimate 0.471
- REVEL 0.27
- MetaLR 0.45
- MetaSVM -0.31
- CADD 25.80
- PolyPhen-2 0.98
- SIFT 0.02
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available