Q78K (p.Gln78Lys) variant of FOS (Protein c-Fos)
Q78K (p.Gln78Lys) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
Q78K (p.Gln78Lys) variant details
- p.Gln78Lys
- gnomAD 14-75279967-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.525
- REVEL 0.39
- MetaLR 0.43
- MetaSVM -0.12
- CADD 25.60
- PolyPhen-2 0.64
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available