Q74K (p.Gln74Lys) variant of FOS (Protein c-Fos)
Q74K (p.Gln74Lys) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
Q74K (p.Gln74Lys) variant details
- p.Gln74Lys
- gnomAD rs1897207496
- Missense
- Variant Prioritization Score for Impact Estimate 0.517
- REVEL 0.41
- MetaLR 0.39
- MetaSVM -0.31
- CADD 22.90
- PolyPhen-2 0.13
- SIFT 0.03
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available