P87S (p.Pro87Ser) variant of FOS (Protein c-Fos)
P87S (p.Pro87Ser) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
P87S (p.Pro87Ser) variant details
- p.Pro87Ser
- TOPMed rs1897208308
- Missense
- Variant Prioritization Score for Impact Estimate 0.486
- REVEL 0.32
- MetaLR 0.42
- MetaSVM -0.44
- CADD 24.30
- PolyPhen-2 1.00
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available