P79T (p.Pro79Thr) variant of FOS (Protein c-Fos)
P79T (p.Pro79Thr) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
P79T (p.Pro79Thr) variant details
- p.Pro79Thr
- gnomAD 14-75279970-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.57
- REVEL 0.52
- MetaLR 0.53
- MetaSVM 0.12
- CADD 25.60
- PolyPhen-2 0.87
- SIFT 0.01
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available
- Literature evidence available