P71S (p.Pro71Ser) variant of FOS (Protein c-Fos)
P71S (p.Pro71Ser) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
P71S (p.Pro71Ser) variant details
- p.Pro71Ser
- gnomAD 14-75279946-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.427
- REVEL 0.26
- MetaLR 0.51
- MetaSVM -0.03
- CADD 23.80
- PolyPhen-2 0.59
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available