P71L (p.Pro71Leu) variant of FOS (Protein c-Fos)
P71L (p.Pro71Leu) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
P71L (p.Pro71Leu) variant details
- p.Pro71Leu
- gnomAD 14-75279947-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.454
- REVEL 0.32
- MetaLR 0.35
- MetaSVM -0.32
- CADD 26.40
- PolyPhen-2 0.71
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available