N7S (p.Asn7Ser) variant of FOS (Protein c-Fos)
N7S (p.Asn7Ser) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
N7S (p.Asn7Ser) variant details
- p.Asn7Ser
- TOPMed rs1341043635
- gnomAD rs1341043635
- Missense
- Variant Prioritization Score for Impact Estimate 0.268
- REVEL 0.05
- MetaLR 0.12
- MetaSVM -1.00
- CADD 20.70
- PolyPhen-2 0.01
- SIFT 0.64
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available