N7K (p.Asn7Lys) variant of FOS (Protein c-Fos)
N7K (p.Asn7Lys) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
N7K (p.Asn7Lys) variant details
- p.Asn7Lys
- gnomAD 14-75279003-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.255
- REVEL 0.09
- MetaLR 0.25
- MetaSVM -0.57
- CADD 22.70
- PolyPhen-2 0.10
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available