M40R (p.Met40Arg) variant of FOS (Protein c-Fos)
M40R (p.Met40Arg) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
M40R (p.Met40Arg) variant details
- p.Met40Arg
- gnomAD 14-75279101-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.19
- MetaLR 0.18
- MetaSVM -0.73
- CADD 24.70
- PolyPhen-2 0.29
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available