L81R (p.Leu81Arg) variant of FOS (Protein c-Fos)
L81R (p.Leu81Arg) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
L81R (p.Leu81Arg) variant details
- p.Leu81Arg
- Ensembl rs1171330070
- Missense
- Variant Prioritization Score for Impact Estimate 0.513
- REVEL 0.53
- MetaLR 0.40
- MetaSVM -0.19
- CADD 26.20
- PolyPhen-2 0.96
- SIFT 0.04
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available