L76P (p.Leu76Pro) variant of FOS (Protein c-Fos)
L76P (p.Leu76Pro) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
L76P (p.Leu76Pro) variant details
- p.Leu76Pro
- gnomAD 14-75279962-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.564
- REVEL 0.54
- MetaLR 0.37
- MetaSVM -0.26
- CADD 32.00
- PolyPhen-2 0.83
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available