L53P (p.Leu53Pro) variant of FOS (Protein c-Fos)
L53P (p.Leu53Pro) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
L53P (p.Leu53Pro) variant details
- p.Leu53Pro
- gnomAD 14-75279893-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.587
- REVEL 0.58
- MetaLR 0.40
- MetaSVM -0.18
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available