L27V (p.Leu27Val) variant of FOS (Protein c-Fos)
L27V (p.Leu27Val) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
L27V (p.Leu27Val) variant details
- p.Leu27Val
- gnomAD 14-75279061-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- REVEL 0.13
- MetaLR 0.31
- MetaSVM -0.71
- CADD 23.40
- PolyPhen-2 0.97
- SIFT 0.16
- Population evidence available
- Structural context available
- Literature evidence available