I67V (p.Ile67Val) variant of FOS (Protein c-Fos)
I67V (p.Ile67Val) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
I67V (p.Ile67Val) variant details
- p.Ile67Val
- gnomAD rs1207749111
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.18
- MetaLR 0.16
- MetaSVM -0.85
- CADD 22.80
- PolyPhen-2 0.02
- SIFT 0.06
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available