I61V (p.Ile61Val) variant of FOS (Protein c-Fos)
I61V (p.Ile61Val) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
I61V (p.Ile61Val) variant details
- p.Ile61Val
- TOPMed rs926276216
- gnomAD rs926276216
- Missense
- Variant Prioritization Score for Impact Estimate 0.27
- REVEL 0.08
- MetaLR 0.04
- MetaSVM -1.03
- CADD 17.80
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available