I61M (p.Ile61Met) variant of FOS (Protein c-Fos)
I61M (p.Ile61Met) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
I61M (p.Ile61Met) variant details
- p.Ile61Met
- ExAC rs778847921
- gnomAD rs778847921
- Missense
- Variant Prioritization Score for Impact Estimate 0.407
- REVEL 0.21
- MetaLR 0.19
- MetaSVM -0.85
- CADD 22.40
- PolyPhen-2 0.48
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available