H31R (p.His31Arg) variant of FOS (Protein c-Fos)
H31R (p.His31Arg) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
H31R (p.His31Arg) variant details
- p.His31Arg
- gnomAD 14-75279074-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.09
- MetaLR 0.14
- MetaSVM -0.91
- CADD 22.20
- PolyPhen-2 0.14
- SIFT 0.34
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available