H31N (p.His31Asn) variant of FOS (Protein c-Fos)
H31N (p.His31Asn) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
H31N (p.His31Asn) variant details
- p.His31Asn
- gnomAD 14-75279073-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.35
- REVEL 0.11
- MetaLR 0.12
- MetaSVM -0.95
- CADD 22.20
- PolyPhen-2 0.10
- SIFT 0.38
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available
- Literature evidence available